Many over-the-counter weight gain supplements are not strictly regulated for efficacy or safety. Some may contain ingredients that can interact with other medications or cause side effects.

Increasing caloric intake through whole foods—such as nuts, avocados, lean proteins, and complex carbohydrates—is often the safest and most effective way to gain weight.

If weight gain is difficult due to an underlying medical condition, a physician may prescribe specific medications to stimulate appetite or manage metabolic issues. These medications are only available at licensed pharmacies with a valid prescription from a doctor.

Before starting any weight gain pill or supplement, consulting with a doctor or a registered dietitian is essential. They can help determine if a supplement is safe for your specific health profile and identify the root cause of being underweight.