The story centers on Steve ( Anthony Mackie ) and Dennis (Jamie Dornan), lifelong friends and paramedic partners in New Orleans.

is a 2019 science fiction horror-thriller that marks the fourth feature collaboration between visionary directors Justin Benson and Aaron Moorhead . The film follows two New Orleans paramedics whose lives are upended by a series of bizarre, otherworldly deaths linked to a new designer drug. Core Premise and Plot

They begin encountering horrific scenes—including spontaneous combustion and exotic snake bites—all connected to a synthetic drug called "Synchronic".