The resulting "energy crisis" triggers the release of inflammatory substances like bradykinin, serotonin, and substance P. These chemicals sensitize local pain receptors, creating the characteristic "exquisite tenderness" and referred pain. 2. Identifying the "Knot"
An excessive leak of ACh causes localized muscle fibers to stay in a state of permanent contraction. Myofascial Trigger Points: Pathophysiology and ...
Myofascial Trigger Points Then and Now: A Historical ... - PMC The resulting "energy crisis" triggers the release of
While research is ongoing, the most widely accepted explanation is the . This theory suggests a "vicious cycle" occurring at the neuromuscular junction: Myofascial Trigger Points: Pathophysiology and ...