: For the first time, white matter characteristics are part of the formal criteria. A diagnosis of probable CAA can now be made with just one lobar hemorrhagic lesion if accompanied by either:
The Boston criteria version 2.0 for cerebral amyloid angiopathy : For the first time, white matter characteristics
: Enlarged fluid spaces in the deep white matter. : For the first time
The v2.0 criteria significantly increase diagnostic sensitivity—capturing more true cases without losing specificity—by broadening the biological markers recognized by MRI. : For the first time, white matter characteristics
: Specific patterns of white matter damage. Clinical Significance