: Unlike most others that target appetite, this blocks about 25% of the fat you eat from being absorbed. 2. Over-the-Counter (OTC) Options
: While many are injectables (like Ozempic), oral versions like Rybelsus (semaglutide) are available. They mimic a gut hormone to make you feel full faster and longer.
: The only FDA-approved OTC weight-loss drug. It is a lower-dose version of the prescription Xenical and works by blocking fat absorption.
Weight Loss Pills in 2025: Your Guide to Types & Effectiveness