DGKK is a member of the type II diacylglycerol kinase family. Its primary role is to convert into phosphatidic acid (PA) .
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: Research indicates DGKK is essential for the development of male external genitalia. 2. DGKK and "Zip" (Zipping Mechanisms) DGKK is a member of the type II diacylglycerol kinase family
: The term "zip" is sometimes used metaphorically to describe the folding of conserved motifs, such as the DGGK motif (highly similar to DGKK), which is essential for the function of certain bacterial enzymes. A Conserved DGGK Motif Is Essential for the
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: In the brain, DGKK is a master regulator of lipid signaling. A loss of its activity is linked to Fragile X Syndrome , leading to dendritic spine abnormalities and behavioral deficits.